KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
26.97
Human Site:
T41
Identified Species:
39.56
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
T41
E
L
L
K
V
L
G
T
G
A
Y
G
K
V
F
Chimpanzee
Pan troglodytes
XP_508900
901
98668
T168
E
L
L
K
V
L
G
T
G
A
Y
G
K
V
F
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
T41
E
L
L
K
V
L
G
T
G
A
Y
G
K
V
F
Dog
Lupus familis
XP_854926
772
85603
T41
E
L
L
K
V
L
G
T
G
A
Y
G
K
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
T41
A
L
L
K
V
L
G
T
G
A
Y
G
K
V
F
Rat
Rattus norvegicus
Q63531
735
82865
Q70
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
Q39
I
E
D
E
A
L
L
Q
K
E
D
I
C
F
V
Chicken
Gallus gallus
Q5F3L1
789
89022
T47
E
L
L
K
V
L
G
T
G
A
Y
G
K
V
F
Frog
Xenopus laevis
P10665
733
82620
Q70
V
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Q75
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
T269
K
I
I
R
V
L
G
T
G
A
Y
G
R
V
F
Honey Bee
Apis mellifera
XP_395099
910
102507
D72
P
A
P
D
Y
D
E
D
R
A
Y
G
K
V
F
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
G39
F
L
V
R
K
V
G
G
K
D
H
N
T
I
Y
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
L43
K
L
Y
A
M
K
V
L
K
K
A
T
I
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
G30
D
E
N
E
K
S
W
G
N
G
L
F
H
F
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
6.6
100
73.3
80
N.A.
66.6
40
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
100
86.6
93.3
N.A.
100
40
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
7
0
0
0
0
50
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
7
7
0
7
0
7
0
7
7
0
0
0
0
% D
% Glu:
44
13
0
13
0
0
7
0
0
7
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
19
7
0
13
69
% F
% Gly:
0
0
0
0
0
0
69
13
63
7
0
69
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
7
% H
% Ile:
7
7
7
0
0
0
0
0
0
0
0
7
7
7
0
% I
% Lys:
13
0
0
57
13
7
0
0
19
7
0
0
63
0
0
% K
% Leu:
0
69
57
0
0
69
7
7
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
0
0
7
0
0
0
% N
% Pro:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
13
0
0
0
0
7
0
0
0
7
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
0
19
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
44
0
0
0
7
7
0
0
% T
% Val:
7
0
7
0
63
7
7
0
0
0
0
0
0
75
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
50
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _